کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3920948 | 1599843 | 2011 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Brachial artery conductance during reactive hyperemia is increased in women with polycystic ovary syndrome Brachial artery conductance during reactive hyperemia is increased in women with polycystic ovary syndrome](/preview/png/3920948.png)
ObjectiveTo examine changes in brachial artery conductance (BAC) during reactive hyperemia in women with polycystic ovary syndrome (PCOS) compared to controls.Study designThis is a pilot case–control study performed at a single academic medical center. Changes in BAC during reactive hyperemia were evaluated in 31 women with PCOS and 11 healthy control women. Fasting glucose, insulin, lipids and androgen levels were also determined. A mixed-effects model was used to compare the PCOS curve to the control curve for change in BAC from baseline during reactive hyperemia.ResultsBody mass index (BMI) and testosterone levels were significantly increased in the PCOS group compared to controls (P < 0.05). In addition, the PCOS group had higher total and LDL cholesterol levels (P = 0.05 and 0.09, respectively). Change in BAC from baseline during reactive hyperemia was significantly increased in the PCOS group compared to controls even after adjusting for age, BMI and LDL cholesterol levels (P < 0.0001). There were no significant differences between the two groups in age, blood pressure, or fasting glucose or insulin levels.ConclusionsBrachial artery conductance during reactive hyperemia is significantly increased in women with PCOS compared to controls and may be a novel early indicator of increased cardiovascular risk in women with PCOS.
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 155, Issue 1, March 2011, Pages 49–53