کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3921326 1599871 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Examination of the association between male gender and preterm delivery
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Examination of the association between male gender and preterm delivery
چکیده انگلیسی

ObjectiveTo examine possible reasons why a male fetus constitutes a risk factor for preterm delivery.Study designRetrospective study of deliveries from hospital database in a UK teaching hospital. The population comprised all deliveries >23 weeks over an 11-year period, excluding multiples, terminations and pregnancies with major abnormalities including indeterminate gender. Obstetric variables and outcomes were initially compared in male and female babies for preterm births in different gestation bands, extreme (<28 weeks), severe (29–32 weeks) and moderate (33–36 weeks). For each, the odds ratios with 95% confidence intervals for preterm delivery were calculated. Then, using binary logistic regression with adjusted odds ratios with 95% confidence intervals, putative causal pathways that might explain the male excess were tested.Results75,725 deliveries occurred, of which 4003 (5.3%) were preterm. Males delivered preterm more frequently (OR 1.13, 95% CI 1.06–1.20). This was due to spontaneous (OR 1.30, 95% CI 1.19–1.42) but not iatrogenic (OR 0.96, 95% CI 0.87–1.05) preterm birth. There was an increased risk of pre eclampsia among preterm females. Although males were larger, and male pregnancies were more frequently nulliparous and affected by some other obstetric complications (abruption, urinary tract infection), these did not account for their increased risk. Any effect of growth restriction could not be properly determined.ConclusionsBeing male carries an increased risk of spontaneous but not iatrogenic preterm birth. The reasons behind this remain obscure.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 141, Issue 2, December 2008, Pages 123–126
نویسندگان
, , ,