کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3923562 1253049 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Watchful Waiting Policy in Recurrent Ta G1 Bladder Tumors
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Watchful Waiting Policy in Recurrent Ta G1 Bladder Tumors
چکیده انگلیسی

ObjectiveTo determine the outcome of a watchful waiting policy in patients suffering from small, recurrent, papillary bladder tumors.MethodsWatchful waiting has been considered an option when a small (<10 mm) papillary, asymptomatic tumor with negative urinary cytology was found on follow-up cystoscopy in patients who had previous resection(s) of superficial, low-grade (Ta) bladder tumor(s). The watchful waiting protocol included cystoscopy and urinary cytology every 3 months for 2 years (and then every 6 months). Surveillance was stopped if the patient had developed either symptoms related to the tumor or positive cytology, or if there had been a significant alteration in tumor morphology or size.ResultsThirty-eight watchful waiting periods were documented in 28 patients (mean age 67.7 years). Mean period length was 13.5 months (SD 14.4 months; range 3–60 months). Thirty periods were terminated with tumor resection. The main reasons for termination of surveillance were the appearance of additional tumors (19 patients) and excessive tumor growth (9 patients). Hematuria indicated tumor removal in only one patient. All resected tumors were stage Ta (23 were grade 1, and 7, grade 2). The rate of tumor growth during the watchful waiting period depended highly on the tumor's largest diameter at the beginning of surveillance. If the initial tumor diameter was smaller than 5 mm (32 cases), the tumor growth rate was 4 ± 5.1 mm3/mo (mean ± SD); if the initial tumor diameter was ≥5 mm (6 cases), the tumor growth rate was 870 ± 1116 mm3/mo (p < 0.05).ConclusionsSmall, recurrent papillary bladder tumors after resection of low-grade Ta tumor(s) pose minimal risk for the patient. A watchful waiting policy— without resection of the tumor—may be considered in these patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Urology - Volume 49, Issue 2, February 2006, Pages 303–307
نویسندگان
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