کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3930890 | 1253279 | 2007 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Continuing Role of PSA in the Detection and Management of Prostate Cancer
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
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چکیده انگلیسی
Despite being used extensively for the diagnosis and management of prostate cancer, prostate-specific antigen (PSA) testing remains controversial. Doubts have been raised over the continued use of PSA in the detection of clinically significant prostate cancer because many men now present with early-stage, small-volume tumours. This article examines the limitations of using a single PSA value in diagnosis and discusses alternative approaches to PSA testing, in particular PSA velocity and PSA doubling time, which are now emerging as valuable pretreatment disease predictors. A clinical scenario is also presented to illustrate the use of PSA kinetics in identifying candidates for biopsy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Urology Supplements - Volume 6, Issue 3, March 2007, Pages 327–333
Journal: European Urology Supplements - Volume 6, Issue 3, March 2007, Pages 327–333
نویسندگان
Kurt Miller, Per-Anders Abrahamsson, Koichiro Akakura, Frans M.J. Debruyne, Christopher P. Evans, Laurence Klotz,