کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3934832 1253390 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of ketorolac on pregnancy rates when used immediately after oocyte retrieval
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
The effect of ketorolac on pregnancy rates when used immediately after oocyte retrieval
چکیده انگلیسی

ObjectiveTo study the effect of ketorolac, a potent anti-inflammatory medication, on in vitro fertilization (IVF) pregnancy outcomes when used at the time of oocyte retrieval.DesignRetrospective review of 454 patients from 2003–2009.SettingTertiary hospital-affiliated fertility center.Patient(s)Consecutive subfertile women undergoing their first IVF cycle.Intervention(s)Ketorolac administration immediately after oocyte retrieval.Main Outcome Measure(s)Pregnancy, implantation, live-birth, and miscarriage rates, and postsurgical visual analog pain score.Result(s)Of the 454 patients undergoing their first IVF cycle for all indications, 103 received intravenous ketorolac immediately after oocyte retrieval, based on anesthesiologist preference. Patient and procedural characteristics were similar between both groups. The use of ketorolac had no effect on the rates of implantation, miscarriage, pregnancy, live birth, or multiple pregnancy. The patients receiving ketorolac experienced statistically significantly less pain.Conclusion(s)This study suggests ketorolac has no apparent detrimental effect on IVF pregnancy outcomes when administered immediately after oocyte retrieval. Ketorolac appears to be a safe and effective analgesic to use at the time of oocyte retrieval.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 100, Issue 3, September 2013, Pages 725–728
نویسندگان
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