کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3935198 1253405 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Safety of uterine and/or ovarian preservation in young women with grade 1 intramucous endometrial adenocarcinoma: a comparison of survival according to the extent of surgery
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Safety of uterine and/or ovarian preservation in young women with grade 1 intramucous endometrial adenocarcinoma: a comparison of survival according to the extent of surgery
چکیده انگلیسی

ObjectiveTo compare the survival of patients with grade 1 intramucous endometrial adenocarcinoma according to the extent of surgery.DesignRetrospective cohort study.SettingNot applicable.Patient(s)A cohort of 489 patients who were 40 years of age or younger with grade 1 intramucous endometrial adenocarcinoma.Intervention(s)The patients were divided into the following three groups: 101 patients who underwent uterine preservation, 184 patients who underwent ovarian preservation, and 204 patients who underwent hysterectomy with oophorectomy.Main Outcome Measure(s)The demographics and survival rates were compared.Result(s)In the multivariate analysis, no factors were associated with ovarian preservation. In the multivariate analysis, the factors that were associated with uterine preservation were a later year of diagnosis and young age. In a multivariate Cox model, ovarian and uterine preservation had no effect on either cancer-specific or overall survival.Conclusion(s)In patients with grade 1 intramucous endometrial adenocarcinoma, uterine and ovarian preservation were not associated with an increase in cancer-related mortality. Longer follow-up is needed to confirm the safety of a conservative approach toward the ovaries and/or the uterus.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 98, Issue 5, November 2012, Pages 1229–1235
نویسندگان
, , , , ,