کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3935727 1253423 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sperm DNA damage and seminal oxidative status after shock-wave lithotripsy for distal ureteral stones
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Sperm DNA damage and seminal oxidative status after shock-wave lithotripsy for distal ureteral stones
چکیده انگلیسی

ObjectiveTo investigate the relationship between level of sperm DNA damage, seminal oxidative status, and shock-wave lithotripsy (SWL) for distal ureteral stones.DesignProspective study with control.SettingAcademic research institute.Patient(s)Men who had undergone SWL for distal and upper ureter stones.Intervention(s)Level of sperm DNA damage and seminal oxidative status assessed through the examination of semen on the day before and 3 days, and 3 months after SWL.Main Outcome Measure(s)DNA damage score and oxidative stress in semen parameters.Result(s)Sperm DNA damage score and semen total oxidant status (TOS) levels increased, but semen total antioxidant status (TAS) levels, sperm concentration, and motility decreased immediately after SWL. However, there were no statistically significant correlations between the DNA damage scores and the increased TAS and TOS levels in the study group. All of the changes returned completely to initial level during three months after SWL.Conclusion(s)SWL may affect fertility in men. Therefore, we suggest other treatment modalities, such as ureteroscopy, for young men with distal ureteral stones to prevent the development of male infertility.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 96, Issue 5, November 2011, Pages 1087–1090
نویسندگان
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