کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3935737 | 1253423 | 2011 | 4 صفحه PDF | دانلود رایگان |

ObjectiveTo demonstrate that the use of donor sperm leads to varying outcome rates and that its use has evolved.DesignRetrospective observational cohort study.SettingUniversity-affiliated private IVF setting.Patient(s)Women (2,934) undergoing donor insemination (DI) or IVF with donor sperm (IVF-D).Intervention(s)None.Main Outcome Measurement(s)We evaluated the distribution of the clinical indications for the use of donated sperm, studying the reproductive outcome.Result(s)A total of 1,663 DI (57%) and 1,271 IVF-D (43%) were performed. There were significant differences in the indications for the use of donated sperm (DI vs. IVF-D). Regarding pregnancy rates (PR), cases of nonobstructive azoospermia presented the highest rate (29.1%), whereas cases of intracytoplasmic sperm injection (ICSI) failures and single women showed rates of 27.6% and 22.6%, respectively. Meanwhile, patients with ICSI failures achieved the highest PRs in IVF cycles (48.7%), whereas nonobstructive azoospermia and single women showed rates of 42.0% and 38.2%, respectively. There have been significant increases in the use of donated sperm in single women.Conclusion(s)Single women, which also represented the oldest group, show a lower probability of achieving pregnancy, and thus represent a subfertile population. Associated factors could include advanced maternal age.
Journal: Fertility and Sterility - Volume 96, Issue 5, November 2011, Pages 1134–1137