کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3937040 | 1253469 | 2009 | 4 صفحه PDF | دانلود رایگان |

ObjectivesTo assess the efficacy, safety, and acceptability of early termination of pregnancy by vaginal administration of a single dose of misoprostol.SettingHealthy women seeking abortion in an institutional research environment in a tertiary-care hospital.DesignProspective randomized controlled clinical trial.ParticipantsOne hundred forty women seeking termination of pregnancy up to 49 days' gestational age were alternatively assigned to undergo medical or suction termination.Intervention(s)Saline-soaked prostaglandin E1 analogue, misoprostol (800 μg), was administered vaginally in group I, and group II underwent suction evacuation. Transvaginal sonography was performed on two subsequent visits to assess outcome.Main Outcome Measure(s)Efficacy, side effects, complications, and acceptability were assessed in both groups.Result(s)Complete abortion rate between the misoprostol and the surgical group was 94.2% versus 95.5%, respectively. Side effects were fewer in the misoprostol group and it had a higher acceptability rate.Conclusion(s)Single dose of vaginal misoprostol alone has a success rate comparable with surgical method for termination of early pregnancy. Side effects were fewer in women who received misoprostol, and the method was well accepted.
Journal: Fertility and Sterility - Volume 91, Issue 1, January 2009, Pages 28–31