Diagnostic accuracy of sperm chromatin dispersion test to evaluate sperm deoxyribonucleic acid damage in men with unexplained infertility

The SCD test is more sensitive than the TUNEL assay for the assessment of DNA damage in men with unexplained infertility. Although the methods are poorly correlated, SCD may discriminate men with normal and abnormal sperm DNA damage with moderate accuracy when compared with TUNEL. It is important to distinguish between the methods because they differently evaluate sperm DNA damage.