کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3938781 1253541 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical pregnancy after uterus transplantation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Clinical pregnancy after uterus transplantation
چکیده انگلیسی

ObjectiveTo present the first clinical pregnancy after uterus transplantation.DesignCase study.SettingTertiary center.Patient(s)A 23-year-old Mayer-Rokitansky-Kuster-Hauser syndrome patient with previous vaginal reconstruction and uterus transplantation.Intervention(s)Eighteen months after the transplant, the endometrium was prepared for transfer of the thawed embryos.Main Outcome Measure(s)Implantation of embryo in an allografted human uterus.Result(s)The first ET cycle with one day 3 thawed embryo resulted in a biochemical pregnancy. The second ET cycle resulted in a clinical pregnancy confirmed with transvaginal ultrasound visualization of an intrauterine gestational sac with decidualization.Conclusion(s)We have presented the first clinical pregnancy in a patient with absolute uterine infertility after uterus allotransplantation. Although the real success is the delivery of a healthy near-term baby, this clinical pregnancy is a great step forward and a proof of concept that the implantation phase works.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 100, Issue 5, November 2013, Pages 1358–1363
نویسندگان
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