کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3938793 1253541 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparative gene expression profiling of adult mouse ovary-derived oogonial stem cells supports a distinct cellular identity
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Comparative gene expression profiling of adult mouse ovary-derived oogonial stem cells supports a distinct cellular identity
چکیده انگلیسی
Freshly isolated OSCs exhibit a germline gene expression profile that overlaps with, but is distinct from, that of PGCs and SSCs. After in vitro expansion, OSCs activate expression of pluripotency genes found in freshly isolated PGCs. In vivo, OSC numbers in the ovaries fluctuate during the estrous cycle, with the highest numbers noted during the luteal phase. This is followed by activation of Stra8 expression during the follicular phase, which may signify a wave of neo-oogenesis to partially offset follicular loss through atresia and ovulation in the prior cycle.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 100, Issue 5, November 2013, Pages 1451-1458.e2
نویسندگان
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