Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility

ObjectiveTo describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility.DesignCase report from a randomized clinical trial.SettingAcademic medical center.Patient(s)A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor.Intervention(s)Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity.Main Outcome Measure(s)Pregnancy.Result(s)A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle.Conclusion(s)The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.