کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3941707 1253622 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Low-dose aspirin use does not improve in vitro fertilization outcomes in poor responders
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Low-dose aspirin use does not improve in vitro fertilization outcomes in poor responders
چکیده انگلیسی

ObjectiveTo assess if aspirin improves pregnancy outcome in patients undergoing in vitro fertilization (IVF) with a diagnosis of poor response.DesignRetrospective cohort analysis.SettingAcademic private practice.Patient(s)1250 poor-responder patients undergoing IVF.Intervention(s)Low-dose (81 mg) aspirin before and during an IVF cycle.Main Outcome Measure(s)Live-birth rate.Result(s)Patients taking 81 mg of aspirin had statistically significantly higher basal antral follicle counts, more days of stimulation, more ampules of gonadotropins used, higher peak estradiol levels, and more follicles that were ≥14 mm in diameter on the day of human chorionic gonadotropin administration. There was a decrease in the overall fertilization rate for the patients taking aspirin. There was no difference in IVF outcome rates (implantation, pregnancy, loss, or live birth).Conclusion(s)Patients with a diagnosis of poor response who were taking a regimen of 81 of mg aspirin showed an increase in many IVF stimulation parameters and a decrease in fertilization rates. No improvement secondary to 81-mg aspirin intake was found in IVF outcome rates.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 89, Issue 5, May 2008, Pages 1113–1117
نویسندگان
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