کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3942544 | 1254014 | 2015 | 5 صفحه PDF | دانلود رایگان |

• Laparoscopic TMMR can be safely performed in selected cervical cancer patients.
• Laparoscopic TMMR has a notable reduction in postoperative functional morbidity.
• The oncological role of the L-TMMR needs further future investigations.
ObjectiveTo analyze the feasibility of total mesometrial resection by laparoscopy (L-TMMR) in a multicentric series of early stage cervical cancer.MethodWe prospectively evaluated a consecutive series of cervical cancer patients with pre-operative FIGO stages IA2–IB1 at the Catholic University in Rome and in Campobasso and the Charitè University in Berlin. All cases were assessed at pre-operative MRI scan and clinically confirmed by investigation under anesthesia, adhering strictly to the FIGO criteria. The surgical and post-surgical data were collected.Results104 women with cervical cancer were admitted between July 2013 and August 2014 and among them 71 patients with pre-operative FIGO stages IA2–IB1 were treated with L-TMMR. One laparotomic conversion was registered. The median operative time was 260 min (120–670 min), estimated blood loss was 100 cm3 (25–900 cm3), and the median length of hospital stay was 6 days (2–26 days). We observed 8 intra-operative complications including a vascular injury of the left internal iliac vein that caused conversion, 6 vesical injuries and 1 ureteral injury managed laparoscopically. Two vescico-vaginal fistula and one hemoperitoneum were observed as major post-operative complications (4.2%).ConclusionL-TMMR can be safely performed in selected cervical cancer patients. Further larger prospective trials are needed to evaluate the oncological outcome of patients undergoing this surgical procedure.
Journal: Gynecologic Oncology - Volume 139, Issue 1, October 2015, Pages 47–51