کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3942561 1254014 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Close relationship between removal of circumflex iliac nodes to distal external iliac nodes and postoperative lower-extremity lymphedema in uterine corpus malignant tumors
ترجمه فارسی عنوان
ارتباط نزدیک بین حذف گره های بیضه کریفتکس تا اندام های بیضه خارجی دیستال و لنفدهم پایین اندام بعد از عمل در تومورهای بدخیم کروی رحم
کلمات کلیدی
نجات یافته از سرطان، لنفادنکتومی، ادم پا، گره حلقوی بیضه، سرطان آندومتری
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی


• Removal of CINDEIN is associated with lower-extremity lymphedema.
• Removal of CINDEIN can be eliminated in patients with endometrial cancer.
• CINDEIN dissection may become obsolete in future treatment of endometrial cancer.

ObjectiveThe aim of this study was to confirm a causal relationship between removal of circumflex iliac nodes to the distal external iliac nodes (CINDEIN) and lower-extremity lymphedema after systematic lymphadenectomy in patients with uterine corpus malignancies.MethodsA retrospective chart review was carried out for all patients with uterine corpus malignant tumor managed at Hokkaido Cancer Center between 1991 and 2013. All 318 patients underwent CINDEIN dissection as a part of initial surgery and 217 patients did not. Patients had undergone hysterectomy, bilateral salpingo-oophorectomy and lymphadenectomy and their medical records were reviewed. The type of lymphadenectomy gradually shifted from pelvic lymphadenectomy with removal of CINDEIN to full lymphadenectomy without CINDEIN dissection during this period. We identified patients with postoperative lower-extremity lymphedema (POLEL). Logistic regression analysis was used to select the risk factors for POLEL.ResultsOf 535 patients evaluated, POLEL was noted in the medical records of 126 patients (23.6%), with median follow-up of 71 months. The occurrence of POLEL was significantly higher in the CINDEIN-dissection group than in the CINDEIN-sparing group (34.3% vs. 7.8%, P < 0.0001). Multivariate analysis confirmed that adjuvant radiation therapy [odds ratio (OR) = 6.3, 95% confidence interval (CI) = 2.6–14.9], resection of more than 31 lymph nodes (OR = 2.0, 95% CI = 1.2–3.5), and removal of CINDEIN (OR = 5.4, 95% CI = 3.1–9.3) were independent risk factors for POLEL.ConclusionsElimination of CINDEIN dissection can be helpful in reducing the incidence of POLEL.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gynecologic Oncology - Volume 139, Issue 1, October 2015, Pages 160–164
نویسندگان
, , , , , , , ,