HOXB8 expression in ovarian serous carcinoma effusions is associated with shorter survival

► HOXB5 and HOXB8 are differentially expressed at various anatomic sites in serous ovarian carcinoma. ► HOXB5 expression is higher in post-chemotherapy disease recurrence effusions compared to pre-chemotherapy primary diagnosis effusions. ► Higher HOXB8 expression in effusions is associated with shorter overall and progression-free survival in serous ovarian carcinoma.