کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3944164 1254180 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
“Surgical Apgar Score” predicts postoperative complications after cytoreduction for advanced ovarian cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
“Surgical Apgar Score” predicts postoperative complications after cytoreduction for advanced ovarian cancer
چکیده انگلیسی

ObjectiveA 10-point “Surgical Apgar Score” (SAS) for predicting postoperative complications after general and vascular operations has recently been developed and validated. We sought to estimate the ability of this metric to predict major postoperative complications in women undergoing ovarian cancer cytoreductive procedures.MethodsAll eligible patients with stage III and IV epithelial ovarian, fallopian tube and primary peritoneal cancer undergoing surgical cytoreduction at our institution between 1999 and 2005 were included. Medical records were reviewed and demographic data, clinicopathologic characteristics, comorbidities and intra and postoperative complications were analyzed. The surgical score was calculated from intraoperative blood loss, lowest mean arterial pressure and lowest heart rate as previously described. Descriptive statistics, univariable and multivariable analyses were used as appropriate. Occurrence of major postoperative complications represented the primary outcome.ResultsA total of 232 cases were analyzed. Mean age was 62 years. Most patients were Caucasian (92%) and diagnosed with stage III disease (83%). Mean duration of surgical procedure was 171 (70–350) minutes. Median SAS was 6 points (range 1–9). On multivariable analyses, occurrence of major postoperative complications was associated with multiple comorbidities (OR 2.2; 95% CI:1.5–3.1; p < 0.0001), stage IV disease (OR 2.5; 95% CI:1.1–5.7; p = 0.03), ASA class (OR 2.4; 95% CI:1.2–4.7; p = 0.01) and SAS ≤ 4 (OR 7.4; 95% CI:2.9–18.8; p < 0.0001).ConclusionsLower SAS (≤ 4) is the most powerful predictor of postoperative complications in patients undergoing cytoreductive surgery for advanced epithelial ovarian cancer. This prognostic tool may prove helpful for triaging such patients to optimal postoperative levels of care and directing counseling, monitoring and management in the postoperative period.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gynecologic Oncology - Volume 116, Issue 3, March 2010, Pages 370–373
نویسندگان
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