کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3944617 1254219 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preoperative quality of life and surgical outcomes in gynecologic oncology patients: A new predictor of operative risk?
ترجمه فارسی عنوان
کیفیت پیش از عمل جراحی و نتایج جراحی در بیماران انکولوژیک زنان: یک پیش بینی جدید در مورد خطر جراحی؟
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی


• Patient-reported pre-operative QoL measures are associated with post-operative outcomes in gynecologic oncology patients.
• Measures of lower functional and physical ability are most strongly correlated with risk of post-operative morbidity and hospital readmissions.
• Identifying QoL deficits pre-operatively can improve patient selection and counseling, and targeting of high-risk patients for pre- and post-operative intervention.

ObjectiveQuality of life (QoL) for women with gynecologic malignancies is predictive of chemotherapy related toxicity and overall survival but has not been studied in relation to surgical outcomes and hospital readmissions. Our goal was to evaluate the association between baseline, pre-operative QoL measures and 30-day post-operative morbidity and health resource utilization by gynecologic oncology patients.MethodsWe analyzed prospectively collected survey data from an institution-wide cohort study. Patients were enrolled from 8/2012 to 6/2013 and medical record data was abstracted (demographics, comorbid conditions, and operative outcomes). Responses from several validated health-related QoL instruments were collected. Bivariate tests and multivariable linear and logistic regression models were used to evaluate factors associated with QoL scores.ResultsOf 182 women with suspected gynecologic malignancies, 152 (84%) were surveyed pre-operatively and 148 (81%) underwent surgery. Uterine (94; 63.5%), ovarian (26; 17.5%), cervical (15; 10%), vulvar/vaginal (8; 5.4%), and other (5; 3.4%) cancers were represented. There were 37 (25%) cases of postoperative morbidity (PM), 18 (12%) unplanned ER visits, 9(6%) unplanned clinic visits, and 17 (11.5%) hospital readmissions (HR) within 30 days of surgery. On adjusted analysis, lower functional well-being scores resulted in increased odds of PM (OR 1.07, 95%CI 1.01–.1.21) and HR (OR 1.11, 95%CI 1.03–1.19). A subjective global assessment score was also strongly associated with HR (OR 1.89, 95%CI 1.14, 3.16).ConclusionLower pre-operative QoL scores are significantly associated with post-operative morbidity and hospital readmission in gynecologic cancer patients. This relationship may be a novel indicator of operative risk.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gynecologic Oncology - Volume 133, Issue 3, June 2014, Pages 546–551
نویسندگان
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