کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3947391 1254431 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fertility-sparing options for early stage cervical cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Fertility-sparing options for early stage cervical cancer
چکیده انگلیسی

ObjectiveTo review the literature on fertility-sparing options for women with early stage cervical cancer and outline patient selection criteria, operative, oncologic, and pregnancy outcomes.MethodsThe literature was searched using MEDLINE (OVID: 1950 through October 2009) and EMBASE (OVID: 1988 through October 2009) using combined disease-specific terms (uterine cervix neoplasms/ or cervi:.ti AND cancer:.ti or neoplasms/ or carcinoma:.ti) with treatment-specific term (trachelectomy/). The search was restricted to English or French language and humans. Additionally, Pubmed was searched with terms “cervix”, “carcinoma”, and “trachelectomy”. Reference lists of related articles and recent review articles were also screened for additional citations.ResultsThe largest data on fertility-sparing procedures in early stage cervical cancer has been reported with radical vaginal trachelectomy (RVT). Other fertility-sparing options have emerged recently, such as radical abdominal trachelectomy (RAT). There have been reports of more conservative methods such as simple trachelectomy or cone biopsy, with or without neoadjuvant chemotherapy.ConclusionsRVT is now well established as a safe and feasible procedure for this patient population, with low morbidity, recurrence, and mortality rates. The use of RAT in selected patients has increased, in addition to more conservative methods such as simple trachelectomy or cone biopsy, with or without neoadjuvant chemotherapy. Continued research in these areas will determine the safety and feasibility of these potential procedures, which will help give more treatment options for young women with early stage cervical cancers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gynecologic Oncology - Volume 117, Issue 2, May 2010, Pages 350–357
نویسندگان
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