کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3947664 1254465 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patterns of inguinal groin metastases in squamous cell carcinoma of the vulva
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Patterns of inguinal groin metastases in squamous cell carcinoma of the vulva
چکیده انگلیسی

Objectives.Assess the pattern of groin node metastases in squamous cell carcinoma (SCC) of the vulva in relation to the site of the primary lesion. Assess whether the identified pattern of lymphatic spread supports the current surgical practice of assessing contralateral nodes for lateral lesions with ipsilateral nodal involvement.Methods.A retrospective study of surgically staged patients with primary SCC of the vulva between 1955 and 1990 was conducted. This cohort of patients was divided in 4 subgroups by location of primary lesion: unilateral, bilateral, midline, and patients with mediolateral lesions. All clinical and pathological data were reviewed and updated to the 1988 TNM vulvar classification.Results.320 patients met the inclusion criteria, and almost all of them (> 95%) underwent bilateral groin assessment. Of the 108 patients with positive groin lymph-node (LN) involvement, 77 presented with unilateral and 24 with bilateral inguinofemoral involvement. Of the 163 patients presenting with only unilateral vulvar lesions, 48 had inguinofemoral node involvement: 37 with ipsilateral-only nodal metastases, 8 with bilateral LN invasion, and only 3 (1.8%) had isolated contralateral nodal metastases. None of these patients with unilateral vulvar lesion that was either ≤ 2 cm in biggest diameter or with invasion ≤ 5 mm had bilateral groin LN involvement at diagnosis.Conclusions.Ipsilateral lymphadenectomy is suitable for patients with unilateral lesions, distant from the midline, and either negative ipsilateral nodes, or with positive ipsilateral LN with lesions smaller than 2 cm.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gynecologic Oncology - Volume 105, Issue 3, June 2007, Pages 742–746
نویسندگان
, , , , , , , ,