کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3951318 | 1600366 | 2011 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Effects of valerian on the severity and systemic manifestations of dysmenorrhea Effects of valerian on the severity and systemic manifestations of dysmenorrhea](/preview/png/3951318.png)
ObjectiveTo evaluate the impact of valerian—a herb with sedative effects and antispasmodic effects on smooth muscles—on the severity of dysmenorrhea.MethodsIn a double-blind, randomized, placebo-controlled trial, 100 students were randomly assigned to receive valerian (n = 49) or placebo (n = 51). Valerian (dose 255 mg) was given 3 times daily for 3 days beginning at the onset of menstruation, for 2 consecutive menstrual cycles. At baseline and during the intervention cycles, the pain severity was evaluated with a visual analog scale and the systemic manifestations were assessed using a multidimensional verbal scale.ResultsThe pain severity at baseline did not differ significantly between the groups. After the intervention, the pain severity was significantly reduced in both groups (P < 0.001), but the extent of the reduction was larger in the valerian group, with the difference between the 2 groups being statistically significant (P < 0.05). The total scores of the systemic manifestations associated with dysmenorrhea decreased after the intervention, but there was no significant difference between the groups, with the exception for syncope (P < 0.05).ConclusionValerian seems to be an effective treatment for dysmenorrhea, probably because of its antispasmodic effects.
Journal: International Journal of Gynecology & Obstetrics - Volume 115, Issue 3, December 2011, Pages 285–288