Perinatal outcome following renal transplantation

ObjectiveTo assess pregnancy outcomes in a population of renal transplant recipients in Mexico.MethodA total of 75 pregnancies in 60 patients managed at the National Institute of Perinatology, Mexico City, Mexico, were reviewed.ResultThe mean age at conception was 26.97 ± 5.42 years and the mean time from transplantation to pregnancy was 5.49 ± 3.6 years. Prepregnancy renal function was determined by serum creatinine level (mean, 1.32 ± 0.73 mg/dL). Prepregnancy hypertension was noted in 45.3% of the patients. Urinary tract infection was the most common complication, followed by pregnancy-induced hypertension. The pregnancy resulted in abortion in 11 patients and in live birth for the remaining 64 participants. The mean ± SD gestational age at birth was 37.1 ± 3 weeks, and intrauterine growth restriction was noted in 12 newborns. A serum creatinine level of 1.5 mg/dL or higher prior to pregnancy was associated with delivery before the 34th week and low birth weight.ConclusionIn this study, pregnancy ended in a live birth in 84% of women with a renal transplant.