کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3953469 1600446 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Gestational age determination and prevention of HIV perinatal transmission
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Gestational age determination and prevention of HIV perinatal transmission
چکیده انگلیسی

Objective: To compare different methods of gestational age (GA) measurement for ensuring effective zidovudine (ZDV) prophylaxis to prevent mother-to-child transmission of HIV. Methods: For 1398 HIV-infected women enrolled in a perinatal prevention trial, gestation durations were calculated based on GA estimated using ultrasound (US), date of last menstruation period (LMP), first fundal height (FH1), and a specific algorithm was developed to provide a “reference” GA. The performance of each GA estimate was evaluated by the percentage of women who would have received ≥ 8 weeks ZDV, if prophylaxis was initiated at 28 weeks. Results: The performances of the algorithm, US, LMP, and FH1 were 95.5%, 94.8%, 88.4%, and 83.7%, respectively. US and FH1 were significantly better when estimated before and after 24 weeks, respectively. Conclusion: In situations where no US is available and LMP is not or imprecisely known, FH1 can be used after 24 weeks to schedule ZDV initiation date.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Gynecology & Obstetrics - Volume 92, Issue 2, February 2006, Pages 176–180
نویسندگان
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