کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3953572 1600371 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Changes in the management and outcome of central nervous system involvement from ovarian cancer since 1994
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Changes in the management and outcome of central nervous system involvement from ovarian cancer since 1994
چکیده انگلیسی

ObjectiveTo identify differences in the management and outcome of patients with central nervous system metastases from epithelial ovarian cancer.MethodsThe clinical and pathologic characteristics, treatment, and outcome of 23 patients with brain metastases from epithelial ovarian cancer who were treated during 1982–1994 were compared with those of 20 patients treated during 1995–2010 at the same center.ResultsNo differences were found in terms of primary tumor characteristics, time interval from ovarian cancer diagnosis to brain involvement diagnosis, sites of metastasis, and presence of extracranial disease. The main difference between the 2 groups was the therapeutic approach. During 1982–1994, most patients received radiotherapy only, whereas most patients during 1995–2010 underwent surgical resection followed by radiotherapy and/or chemotherapy. The duration of survival during 1982–1994 was 5 months, which was significantly shorter than the duration of survival (18 months) during 1995–2010.ConclusionAn aggressive multimodal treatment approach might prolong the survival of patients with brain involvement from ovarian cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Gynecology & Obstetrics - Volume 114, Issue 2, August 2011, Pages 133–136
نویسندگان
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