کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3956851 1255342 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quantifying Electrosurgery-Induced Thermal Effects and Damage to Human Tissue: An Exploratory Study with the Fallopian Tube as a Novel In-Vivo In-Situ Model
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Quantifying Electrosurgery-Induced Thermal Effects and Damage to Human Tissue: An Exploratory Study with the Fallopian Tube as a Novel In-Vivo In-Situ Model
چکیده انگلیسی

ObjectiveTo develop a human in vivo in situ model for analyzing the extent and the basic mechanisms of thermal spread and thermal tissue damage.DesignProspective, open, uncontrolled, nonrandomized, single-center exploratory study.SettingUniversity hospital.PatientsEighteen adult patients undergoing open abdominal hysterectomy for benign disease.InterventionsUnilateral fallopian tube tissue desiccation (10 seconds) with a laparoscopic bipolar clamp at routine settings.Main Outcome MeasuresDeep tissue temperature (thermal probe), tissue surface temperature (thermal camera), and gross and histologic assessments of lesions with a newly developed composite scoring system.ResultsFifteen specimens from 18 patients were evaluated. Lateral thermal damage (LTD; determined by lactate dehydrogenase staining), was strongly correlated with maximum desiccation temperature. Deep tissue LTD and surface LTD were linearly related. Histologic and macroscopic criteria for thermal effects and damage and the corresponding scores proved functional and strongly correlated with LTD. Measurement of deep tissue and tissue surface temperatures consistently yielded complete temporal and spatial temperature distributions that were describable by the heat equation.ConclusionsOur novel in vivo in situ model allows standardized, reproducible, quantitative assessment of electrosurgery-induced thermal effects and damage in human tissue. It will likely provide further insight into the underlying biothermomechanics and may prove useful in the development of safety guidelines for laparoscopic electrosurgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Minimally Invasive Gynecology - Volume 17, Issue 1, January 2010, Pages 70–77
نویسندگان
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