Clinical Effectiveness of Transcervical Polyp Resection in Women with Endometrial Polyps: Randomized Controlled Trial

Study ObjectiveTo estimate the clinical effectiveness of transcervical resection of endometrial polyps.DesignRandomized controlled trial (Canadian Task Force classification I).SettingUniversity teaching hospital.PatientsOne hundred fifty premenopausal women with endometrial polyps.InterventionsEither transcervical resection of the polyp or observation for 6 months.Measurements and Main ResultsThere was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11–1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p <.001). Data were analyzed according to the principle of intention to treat.ConclusionTranscervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women.