Evaluation of Circulating Antisperm Antibody in Infertile Women with Polycystic Ovary Syndrome

ObjectiveTo evaluate levels of the circulating antisperm antibody (ASA) in infertile women with polycystic ovary syndrome (PCOS).MethodsForty-six infertile women with PCOS were enrolled into this study. The serum was screened by the indirect immunobead test for ASA type IgG and IgA according to the WHO laboratory manual.ResultsOf the 46 patients assessed for ASA-IgG, 3 cases had immunobead binding which were 20%, 27% and 35%, respectively, and the sub-positive rate was 6.5%. No case had the clinical positive level according to the WHO criteria (50% or more of the motile sperm with immunobead binding). ASA-IgA was not detected in all cases.ConclusionsThe circulating ASA is not associated with the pathogenesis of infertile women with PCOS.