کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3965294 | 1255898 | 2010 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Changes in Genital Anatomy and Microbiology in Girls between Age 6 and Age 12 Years: A Longitudinal Study Changes in Genital Anatomy and Microbiology in Girls between Age 6 and Age 12 Years: A Longitudinal Study](/preview/png/3965294.png)
Study ObjectiveTo study changes in genital anatomy and occurrence of human papillomavirus and Gardnerella vaginalis in girls resulting from growth and development.DesignAt age 11–12 years, an invitation was sent to 180 girls to attend a follow-up examination. All girls had previously participated in a study exploring anogenital anatomy and microbiology in children selected for non-abuse at age 5 and 6. The genital area was examined with a colposcope and microbiological samples for Gardnerella vaginalis (GV) and human papillomavirus (HPV) were collected. GV was identified by conventional criteria and HPV by a PCR method.ResultsThirty-one girls were examined twice, at mean age 5.7 and 12.0 years. At first examination all were pre-pubertal. At second examination 21 girls were B2/P2 or above. Significantly more girls had developed a structure called a fossa groove. A thick and redundant hymen with a tendency of folding outward was more common at the second examination. Two girls had GV and one girl had HPV-16 identified. Another girl was classified to have a deep notch and a probable transection in her hymen, and this girl reported a painful insertion of a tampon. All girls denied sexual activity.ConclusionThe main genital finding in girls entering puberty is the hymen becoming thick and redundant with a tendency of folding out. In the study findings associated with sexual activity were discovered in two girls, and the possibility of alternative explanations is discussed.
Journal: Journal of Pediatric and Adolescent Gynecology - Volume 23, Issue 2, April 2010, Pages 77–85