Metformin for adolescents with polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age characterized by chronic anovulation, hyperhandrogenism, and is increasingly recognized as a disease developed in adolescent period. The management of adolescents with PCOS is a difficult challenge. The objective of the review was to provide an overview on the effects of metformin for adolescents with PCOS.