Tumor trofoblástico epitelioide de presentación en la posmenopausia

Epithelioid trophoblastic tumor (ETT) is an uncommon neoplasm with low malignant potential derived from chorionic-type intermediate trophoblast. Most ETT arise during the reproductive years following normal pregnancy, an abortion or, rarely, a complete hydatidiform mole. We report the case of a 63-year-old woman who complained of uterine bleeding. Menopause had occurred at the age of 45 and the patient's last documented obstetric antecedent was a normal pregnancy with full-term delivery at the age of 33 years. A well-circumscribed lesion located in the endocervix with histological characteristics of ETT was detected. At diagnosis, the patient presented a mild increase of beta-human chorionic gonadotrophin (18.7 U/mL), which returned to normal levels after hysterectomy. Four years after surgery, the patient is alive with no evidence of disease. In conclusion, trophoblastic lesions should be included in the differential diagnosis of uterine bleeding in the late menopause.