Tumor fibroso solitario de la vulva

Solitary fibrous tumour (SFT) is a rare mesenchymal tumour initially identified in the pleura, but that can be present in virtually all regions. Isolated cases arising in the female genital tract have been described in recent years. We report the case of a woman aged 35 who presented with a vulvar tumour, which was resected. On pathological examination the tumour measured 20 mm in diameter and showed typical features of SFT, consisting of spindle cell proliferation without atypia, alternating with hyper- and hypo-cellular areas, presence of abundant collagen and with a vascular hemangiopericytomatous pattern. Immunohistochemistry was strongly positive for CD34 and bcl-2 and negative for S-100 and actin. SFT shows aggressive behaviour in approximately 25% of cases and should always be considered a potentially malignant tumour, and requires a clinical follow-up. Therefore, the identification and differentiation from other lesions with similar features in the female genital area is essential.