کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3970199 | 1256709 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Short follicular phase of stimulation following corifollitropin alfa or daily recombinant FSH treatment does not compromise clinical outcome: a retrospective analysis of the Engage trial
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
During ovarian stimulation for assisted reproduction, some women respond earlier than others to treatment with follicle-stimulating agents and require fewer days of treatment. To evaluate whether such short stimulation jeopardizes the chance of pregnancy, clinical outcomes of early responders and normal responders were compared in women aged 18-36Â years treated with either a single dose of corifollitropin alfa (756 women) or daily recombinant FSH (750 women) for the first 7Â days of stimulation. On average, about 25% of the evaluated women were early responders. The initial ovarian response was higher in early responders than in normal responders but the number of eggs retrieved and the ongoing pregnancy rates in early and normal responders were similar regardless of the treatment group. This study shows that the chance of ongoing pregnancy was not compromised in women requiring only 1Â week of stimulation compared with women who required a longer duration of stimulation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive BioMedicine Online - Volume 28, Issue 4, April 2014, Pages 462-468
Journal: Reproductive BioMedicine Online - Volume 28, Issue 4, April 2014, Pages 462-468
نویسندگان
Tonko MardeÅ¡iÄ, Bernadette Mannaerts, Mostafa Abuzeid, Michael Levy, Han Witjes, Bart C.J.M. Fauser, Engage investigators Engage investigators,