کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3974082 1256965 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neonatal hemolysis and risk of bilirubin-induced neurologic dysfunction
ترجمه فارسی عنوان
همولیز نوزادان و اختلال عملکرد عصبی ناشی از بیلی روبین
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی

SummaryThe pathologic phenotype of severe hyperbilirubinemia in the newborn infant is primarily due to excessive bilirubin production and/or impaired conjugation, resulting in an increased bilirubin load. This may, in turn, increase an infant's risk for the development of bilirubin-induced neurologic dysfunction (BIND). The highest-risk infants are those with increased bilirubin production rates due to hemolysis. Several immune and non-immune conditions have been found to cause severe hemolysis, and these are often exacerbated in those infants with perinatal sepsis and genetic predispositions. Therefore, identification of these infants, with novel technologies, is paramount in reducing the incidence of BIND and the long-term neurologic sequelae for these at-risk infants.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Fetal and Neonatal Medicine - Volume 20, Issue 1, February 2015, Pages 26–30
نویسندگان
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