کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3974770 1257019 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Corticosteroids in perinatal medicine: How to improve outcomes without affecting the developing brain?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Corticosteroids in perinatal medicine: How to improve outcomes without affecting the developing brain?
چکیده انگلیسی
Antenatal glucocorticoid therapy remains one of the most striking successes in the perinatal management of complicated pregnancies that result in premature birth. The anti-inflammatory and maturative properties of fluorocorticoids are such that all women at risk of preterm delivery before 34 weeks gestation should be treated. Betamethasone is preferred to dexamethasone and no more than two courses, 2 weeks apart, should be given until the evidence from further controlled trials on repeated doses becomes available. In particular, the early use of postnatal dexamethasone should be avoided in preterm infants because of the deleterious effects on neurological development, including not only cerebral palsy but also cognitive function and psychiatric-related behavior. Treatment with other steroids should be restricted to the context of randomized controlled trials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Fetal and Neonatal Medicine - Volume 12, Issue 4, August 2007, Pages 273-279
نویسندگان
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