Efficacy of Intravitreal Ocriplasmin on Vitreomacular Traction and Full-Thickness Macular Holes

In clinical practice, intravitreal injection of ocriplasmin achieved VMT release in approximately one half of treated eyes, with a 27% closure rate for full-thickness MH. Transient ellipsoid changes were evident in 26% of treated eyes, more common in eyes with successful VMT release.