Transepithelial Riboflavin/Ultraviolet. A Corneal Cross-linking in Keratoconus: Morphologic Studies on Human Corneas

Histologic and immunohistochemical findings on human keratoconic corneas showed the presence of biochemical and morphologic alterations in the epithelium and the upper stroma that are significantly improved 3 months after transepithelial CXL. However, further studies are necessary to assess to what extent these results correlate with measurable biomechanical effects.