Corneal Cross-linking: Intrastromal Riboflavin Concentration in Iontophoresis-Assisted Imbibition Versus Traditional and Transepithelial Techniques

Corneal cross-linking transepithelial iontophoresis imbibition yielded greater and deeper riboflavin saturation with respect to conventional epi-on, while maintaining the advantages of avoiding epithelial removal and shorter procedure time, but did not reach concentrations obtained with standard epi-off.