Peripapillary Retinal Nerve Fiber Layer Thickness in Sickle-Cell Hemoglobinopathies Using Spectral-Domain Optical Coherence Tomography

Nonglaucomatous, black sickle-cell patients with focal macular thinning on spectral-domain optical coherence tomography have significantly thinner peripapillary RNFL than those without macular thinning or controls. The degree of thinning correlates with severity of temporal macular thinning. These patients may require different peripapillary RNFL thickness thresholds for future glaucoma evaluations.