The Short-term Effects of Antioxidant and Zinc Supplements on Oxidative Stress Biomarker Levels in Plasma: A Pilot Investigation

This pilot interventional study shows that a 5-day course of antioxidant and zinc supplements can modify plasma levels of CySS, suggesting that this oxidative stress biomarker could help predict how likely an individual is to benefit from AREDS supplementation. Further, CySS may be useful for the evaluation of new AMD therapies, particularly those hypothesized to affect redox status.