کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4003629 1602179 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Identification of New Pathogens in the Intraocular Fluid of Patients With Uveitis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی چشم پزشکی
پیش نمایش صفحه اول مقاله
Identification of New Pathogens in the Intraocular Fluid of Patients With Uveitis
چکیده انگلیسی

PurposeTo determine infectious causes in patients with uveitis of unknown origin by intraocular fluids analysis.DesignCase-control study.MethodsOcular fluids from 139 patients suspected of infectious uveitis, but negative for herpes simplex virus, varicella-zoster virus, cytomegalovirus, and Toxoplasma gondii by polymerase chain reaction and/or antibody analysis in intraocular fluids, were assessed for the presence of 18 viruses and 3 bacteria by real-time polymerase chain reaction (PCR). The ocular fluids from 48 patients with uveitis of known etiology or with cataract were included as controls.ResultsPositive PCR results were found for Epstein-Barr virus, for rubella virus, and for human herpesvirus 6 each in 1 patient and for human parechovirus in 4 patients. Of the human parechovirus–positive patients, 1 was immunocompromised and had panuveitis. The other 3 patients were immunocompetent and had anterior uveitis, all with corneal involvement.ConclusionsHuman parechovirus might be associated with infectious (kerato)uveitis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Ophthalmology - Volume 150, Issue 5, November 2010, Pages 628–636
نویسندگان
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