Topical Interferon Alfa-2b for the Treatment of Recalcitrant Ocular Surface Squamous Neoplasia

Topical IFN-α2b is an important treatment modality for recalcitrant OSSN; it avoids the risks of further limbal stem cell destruction from other agents and surgical excision. If invasive disease is diagnosed at any stage, topical therapy is contraindicated, necessitating surgical excision.