Optical Coherent Tomography Features of Malattia Leventinese

PurposeMalattia leventinese (ML) is an inherited macular degeneration characterized by the presence of large paracentral and small radial drusen. Our purpose was to describe optical coherent tomography (OCT) features observed in ML.DesignProspective observational case series.MethodsTen eyes from five patients with ML aged 27 to 44 years were prospectively included. Best-corrected visual acuity, fundus color photography of the retina, and OCT were performed in each patient.ResultsOCT revealed a hyperreflective thickening of the retinal pigment epithelium–Bruch membrane complex, associated with localized dome-shaped elevations. Retinal thickness above the drusen ranged from 221 to 292 μm (mean 260 μm). Foveal thickness ranged from 72 to 200 μm (mean 144 μm)ConclusionsThe large paracentral drusen presented either as a thickening of the retinal pigment epithelium–Bruch complex or as local limited elevation of retinal pigment epithelium–Bruch complex, both associated with preservation of the neurosensory retina.