Wavefront aberrations in eyes with decentered ablations

PurposeTo compare the refractive and functional outcomes and wavefront profiles in eyes with decentered ablations and eyes with well-centered ablations.SettingMedical Research Foundation, Chennai, Tamil Nadu, India.MethodsThis retrospective analysis comprised eyes with topographically diagnosed decentered ablations after laser in situ keratomileusis (LASIK). Refraction, contrast sensitivity, and ocular wavefront aberrations were measured preoperatively and 1 month postoperatively. The induced aberrations in these eyes were compared with those in eyes with well-centered ablations.ResultsForty-six eyes (38 patients) had decentered ablations and 60 eyes (32 patients), well-centered ablations. The mean decentration in the study group was 0.86 mm ± 0.29 (SD) (range 0.35 to 1.61 mm). There was no significant correlation between decentration and attempted refractive correction. There was, however, a statistically significant (P<.05) linear correlation between the distance of decentration and the magnitude of induced tilt (r = −0.31), coma (r = −0.41), and secondary astigmatism (r = 0.36). The induced changes in tilt, oblique astigmatism, vertical coma, and spherical aberration were statistically significantly higher in eyes with decentered ablations than in eyes with well-centered ablations. A statistically significantly higher percentage of eyes (87%) with well-centered ablations than eyes with decentered ablations (70%) had a postoperative uncorrected visual acuity (UCVA) of 20/20 or better. There was no significant difference in contrast sensitivity between groups.ConclusionEyes with decentered ablations had a significantly higher magnitude of induced aberrations and lower UCVA than eyes with well-centered ablations.