کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4022911 | 1602758 | 2015 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Comparison of the effect of cycloplegic versus NSAID eye drops on pain after photorefractive keratectomy Comparison of the effect of cycloplegic versus NSAID eye drops on pain after photorefractive keratectomy](/preview/png/4022911.png)
PurposeTo compare the effect of Homatropine and Diclofenac eye drops for reducing pain after photorefractive keratectomy (PRK).MethodsThis randomized, double-masked, interventional study included 32 patients (64 eyes) who underwent bilateral PRK. After operation, patients received Homatropine eye drops in one eye and Diclofenac eye drops in the fellow eye for 48 h. The level of pain was evaluated using visual analogue scale (VAS), verbal rating scale (VRS), and pain rating index (PRI) at 0.5, 24, and 48 h after operation.ResultsThe level of pain was statistically similar between the two eyes half an hour after operation; however, Diclofenac eyes had significantly less pain 24 h after operation (1.7 ± 1.4 vs 5.8 ± 2.1, P < 0.001 for VAS, 0.6 ± 0.6 vs 2.4 ± 1.1, P < 0.001 for VRS, and 3.4 ± 3.4 vs 12.0 ± 6.9, P < 0.001 for PRI, respectively). Also, 48 h after surgery, the pain scores were less in the Diclofenac eyes (1.6 ± 1.8 vs 3.4 ± 2.8, P < 0.001 for VAS, 0.6 ± 0.6 vs 1.2 ± 0.9, P < 0.001 for VRS, and 3.3 ± 3.7 vs 6.5 ± 6.2, P < 0.001 for PRI). No case with delayed epithelial healing in both groups was observed.ConclusionThe effect of Homatropine seems to be lower compared to Diclofenac for reducing pain after photorefractive keratectomy.
Journal: Journal of Current Ophthalmology - Volume 27, Issues 3–4, September–December 2015, Pages 87–91