Évaluation en pratique clinique des nouvelles stratégies de dépistage des maculopathies toxiques au plaquénil, selon les nouvelles recommandations de l'American Academy of Ophthalmology. Étude prospective monocentrique à propos de 184 patients

The significant correlation between cumulative HCQ dose, considered as the main risk factor for maculopathy, and positive SD-OCT and 10.2 visual field results render the combination of these two tests the basis of the screening strategy for plaquenil maculopathy. These results suggest using a simplified screening procedure, including annual SD-OCT and 10.2 visual field while taking the cumulative dose into account. Multifocal ERG seems more helpful for diagnostic confirmation than screening, especially for the preclinical stage. Fundus autofluorescence is not an efficient test for early diagnosis.