Small Choroidal Melanoma with Chromosome 3 Monosomy on Fine-Needle Aspiration Biopsy

Using FNAB at the time of plaque radiotherapy, monosomy 3 was found in approximately 27% of small choroidal melanomas, more often in older patients and tumors with documented growth. Transvitreal biopsy into the tumor apex provided better yield compared with transscleral biopsy into the tumor base.