Asymmetry of Right versus Left Intraocular Pressures over 24 Hours in Glaucoma Patients

In this group of untreated glaucoma patients, the strength of association between the right and left eye mean IOPs is only moderate. Residual values of ≥3 mmHg were more common using a symmetric model than with a best-fit model. The current method of performing monocular therapeutic trials in glaucoma patients is unreliable, but it may be possible to improve reliability by using several IOP measurements obtained at different times of the day instead of a single office measurement.