کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4032643 1603022 2012 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Vitreomacular Adhesion and Neovascular Age-Related Macular Degeneration
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی چشم پزشکی
پیش نمایش صفحه اول مقاله
Vitreomacular Adhesion and Neovascular Age-Related Macular Degeneration
چکیده انگلیسی

We explore the hypothesis that vitreomacular adhesion (VMA) and vitreomacular traction (VMT) play a role in the pathogenesis and clinical course of neovascular (“wet”) age-related macular degeneration (AMD). Several biological theories are offered to explain this possible association, including direct tractional force, altered vitreous oxygenation, altered diffusion coefficients of intravitreal molecules, and alterations in the pharmacokinetics of intravitreal drugs. Release of VMT may improve the clinical course of neovascular AMD, and a few case series suggest that vitrectomy can lead to both a functional and anatomic improvement. A large, randomized, controlled clinical trial is underway, investigating pharmacologic release of VMA in eyes with neovascular AMD.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Survey of Ophthalmology - Volume 57, Issue 6, November–December 2012, Pages 498–509
نویسندگان
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