Endogenous candida endophthalmitis in South Taiwan: A 10-year retrospective study

PurposeTo investigate the clinical manifestations and the results of the management of endogenous candida endophthalmitis (ECE) at our hospital.MethodsThis study was a retrospective chart review conducted between September 2002 and September 2012.ResultsOur study included 24 eyes of 14 patients. The culture results revealed Candida albicans in 11 cases and Candida tropicalis in three cases. Diabetes mellitus, cancer, and intravenous catheter implantation were the most important risk factors for ECE. A systemic antifungal agent combined with intravitreal injection or vitrectomy was our method for treating these cases and the complications. The outcomes were generally poor, with a final visual acuity (VA) of better than 0.1 in 10 cases, counting finger to 0.1 in six cases, light perception to hand motion in six cases, and no light perception in two cases.ConclusionUnsatisfactory visual outcome in ECE is related to poor initial VA and complications. Early diagnosis and prompt treatment are necessary for these patients.